VSV G pseusdotyped retroviral vectors

US5817491A · kind A · utility

Assignees

• The Regents of the University of California · US
• Chiron Viagene, Inc. · US

Inventors

• Jiing-Kuan Yee · Arcadia, US
• Nobuhiko Emi · Lomita, US
• Theodore Friedmann · Village of La Jolla, US
• Douglas J. Jolly · Encinitas, US
• Jack R. Barber · San Diego, US

Key dates

• Filing date: Dec 22, 1994
• Grant date: Oct 6, 1998
• Expiry date: Dec 22, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16222
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An enveloped vector particle contains gag and pol proteins from a retrovirus, a nucleic acid sequence and an envelope that includes VSV G envelope glycoprotein. The vector particle can be used to introduce nucleic acids into cells.