Modified factor VII
US5817788A · kind A · utility
64Cited by
9References
9Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 24, 1994 |
| Grant date | Oct 6, 1998 |
| Priority date | — |
| Expiry date | Oct 24, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21021
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modifications render Factor VIIa substantially unable to activate plasma Factors X or IX. Pharmaceutical compositions of the modified Factor VII are used to treat a variety of coagulation-related disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.