Lyophilization closure assembly for a medicament container for use during a lyophilization process
US5819964A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 4, 1997 |
| Grant date | Oct 13, 1998 |
| Priority date | — |
| Expiry date | Apr 4, 2017 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB65D51/241
- WIPO fieldHandling
- WIPO sectorMechanical engineering
Abstract
A lyophilization closure assembly for a container or vial is disclosed. The lyophilization closure assembly is self-supporting with the container and may be employed with the container during a lyophilization process, eliminating the need for a separate crimping operation outside of the sterile environment in which lyophilization is conducted. The lyophilization closure assembly includes a body with a skirt disposed around the rim of the container. The skirt features one or more deflectable abutments and one or more deflectable latches positionable about the rim of the container, and defines one or more vapor passages. An elastomeric closure is retained within the body for sealing the open top of the medicament container. The elastomeric closure features a plug for sealing the open top of the container and a top surface facing away from the open top of the container. The body defines an opening over the elastomeric closure that delimits an access area on the top surface of the closure. A membrane is removably secured over the access area of the elastomeric closure and hermetically encloses the access area.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.