Endothelin receptor antagonists

US5821256A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Dieter Dorsch · Ober-Ramstadt, DE
• Mathias Osswald · Zwingenberg, DE
• Werner Mederski · Zwingenberg, DE
• Claudia Wilm · Darmstadt, DE
• Claus J. Schmitges · Groß-Umstadt, DE
• Maria Christadler · Darmstadt, DE

Key dates

• Filing date: Aug 15, 1996
• Grant date: Oct 13, 1998
• Expiry date: Aug 15, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and X have the meaning indicated in claim 1, and their salts exhibit endothelin receptor-antagonistic properties.