Inhibitors of cell-mediated disorders
US5821265A · kind A · utility
1Cited by
3References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 11, 1997 |
| Grant date | Oct 13, 1998 |
| Priority date | — |
| Expiry date | Jun 11, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L24/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for blocking a cellular proton pump that comprises contacting a cell with a cellular proton pump-blocking effective quantity of In-EDTA or Tl-EDTA. The present invention also provides a method of treating or preventing cell-mediated disorders in a vertebrate animal by administering In-EDTA or Tl-EDTA to the vertebrate animal, as well as a method for stopping the cellular proton pump-blocking effect of Group IIIa metals such as Ga, In, and Tl, through use of suitable chelating agents. Suitable compositions for use in the aforementioned methods are provided as well.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.