Patent · US Expired

Disposable package for use in aerosolized delivery of drugs

US5823178A · kind A · utility

131Cited by
36References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 2, 1996
Grant dateOct 20, 1998
Priority date
Expiry dateAug 2, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2230/40
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A disposable package, tape, and cassette are provided which makes it possible to hold and disperse therefrom liquid, flowable formulations including aqueous formulations (solutions or dispersions with particles less than 0.25 microns in diameter) of a pharmaceutically active drug. In one embodiment formulation is packaged in individual dosage unit containers which containers are preferably interconnected. The package is designed to be integrated into a cassette which can be loaded into a dispersing device capable of individually opening dosage unit containers and aerosolizing the contents through a porous membrane, into a mouth piece on the cassette, for delivery to a patient. In addition to and alongside of each porous membrane, the package may include one or more openings through which air is forced in order to aid in avoiding the accumulation of aerosolized particles. The package may be configured so that the formulation is held in a container not positioned directly vertical to and below the porous membrane, thus making it necessary to channel formulation horizontally to the porous membrane and making it possible to include a vibrating mechanism directly below a chamber covered…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.