Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof
US5824297A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 1, 1993 |
| Grant date | Oct 20, 1998 |
| Priority date | — |
| Expiry date | Sep 1, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for inhibiting cytotoxic poisoning of normal cells in a subject which comprises administering to the subject an amount of a Transforming Growth Factor Beta effective to slow the growth of normal cells and thereby inhibit the cytotoxic poisoning of the normal cells in the subject. Typically, administration is topical and initiated prior to anti-neoplastic therapy such as radiation treatment or chemotherapy. The invention is particularly suited for pediatric patients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.