Patent · US Expired

Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof

US5824297A · kind A · utility

13Cited by
11References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 1, 1993
Grant dateOct 20, 1998
Priority date
Expiry dateSep 1, 2013

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a method for inhibiting cytotoxic poisoning of normal cells in a subject which comprises administering to the subject an amount of a Transforming Growth Factor Beta effective to slow the growth of normal cells and thereby inhibit the cytotoxic poisoning of the normal cells in the subject. Typically, administration is topical and initiated prior to anti-neoplastic therapy such as radiation treatment or chemotherapy. The invention is particularly suited for pediatric patients.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.