Patent · US Expired

Detection of mismatches by cleavage of nucleic acid heteroduplexes

US5824471A · kind A · utility

32Cited by
3References
30Claims
0Family size

Assignees

Inventors

Key dates

Filing dateJun 5, 1995
Grant dateOct 20, 1998
Priority date
Expiry dateJun 5, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/683
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Novel methods and kits for detecting mismatches in nucleic acids using one or more resolvase enzymes. These methods can be used in medical procedures or research, veterinary procedures or research, agricultural applications, forensics, and paternity testing. For example, in forensics and paternity testing, methods of the invention can replace or complement RFLP mapping.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.