Adenovirus vectors for gene therapy
US5824544A · kind A · utility
122Cited by
0References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 6, 1995 |
| Grant date | Oct 20, 1998 |
| Priority date | — |
| Expiry date | Oct 6, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10343
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel adenovirus vectors for use in gene therapy which are designed to prevent the generation of replication-competent adenovirus (RCA) during in vitro propagation and clinical use. The invention also provides methods for the production of the novel virus vectors. These vectors maximize safety for clinical applications in which adenovirus vectors are used to transfer genes into recipient cells for gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.