Branched hydrazone linkers
US5824805A · kind A · utility
167Cited by
27References
13Claims
0Family size
Inventors
Key dates
| Filing date | Dec 19, 1996 |
| Grant date | Oct 20, 1998 |
| Priority date | — |
| Expiry date | Dec 19, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/252
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Branched hydrazone linkers for linking a targeting ligand such as an antibody to a therapeutically active drug. The point of branching is at a polyvalent atom and the number of drugs increases by a factor of two for each generation of branching. A preferred drug is doxorubicin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.