.beta.-galactoside-.alpha.-2, 6-sialyltransferase, and a process for producing from Photobacterium
US5827714A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 28, 1996 |
| Grant date | Oct 27, 1998 |
| Priority date | — |
| Expiry date | Oct 28, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/822
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A .beta.-galactoside-.alpha.-2,6-sialyltransferase derived from a microorganism belonging to the genus Photobacterium has ben disclosed, having the following physicochemical properties: (1) action and specificity: transferring sialic acid from cytidine monophosphate-sialic acid to the 6-position of a galactose residue in a sugar chain of a glycoconjugate or in a free sugar chain, or to the 6-position of a monosaccharide having a hydroxyl group on carbon at the 6-position and being capable of forming a glycoconjugate. (2) optimum pH: 5 to 6; (3) optimum temperature: 30.degree. C.; and (4) molecular weight: 64,000.+-.5,000 (determined by gel filtration).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.