Patent · US Expired

P-selectin ligand protein

US5827817A · kind A · utility

78Cited by
2References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateOct 27, 1998
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/24
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.