Method for screening for agents which increase telomerase activity in a cell
US5830644A · kind A · utility
8Cited by
2References
10Claims
0Family size
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Key dates
| Filing date | Nov 12, 1993 |
| Grant date | Nov 3, 1998 |
| Priority date | — |
| Expiry date | Nov 12, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to increase or decrease telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity and means are shown for slowing or reversing the loss of telomeric repeats in aging cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.