Patent · US Expired

SOK-1 and methods of use

US5830699A · kind A · utility

2Cited by
0References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 7, 1997
Grant dateNov 3, 1998
Priority date
Expiry dateMay 7, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A SOK polypeptide, an isolated DNA having a nucleotide sequence encoding a SOK polypeptide, and a method of determining whether a candidate compound modulates SOK-1 activity or expression, comprising the steps of providing a first and a second recombinant cell expressing a SOK gene; introducing a candidate compound into the first cell, but not into the second cell; measuring a SOK function in the first and second cells; and comparing the results obtained with the first and second SOK transformed cells, wherein an increase or decrease in the SOK function in the first cell compared to the second cell is an indication that the candidate compound modulates SOK expression or activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.