Steroid sulphatase inhibitors
US5830886A · kind A · utility
12Cited by
0References
9Claims
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Key dates
| Filing date | Jun 2, 1995 |
| Grant date | Nov 3, 1998 |
| Priority date | — |
| Expiry date | Jun 2, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/0072
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Steroid sulphatase inhibitors and pharmaceutical compositions containing them for use in the treatment of oestrone dependent tumors, especially breast cancer. The steroid sulphatase are sulphamate esters of formula (I): ##STR1## where R.sub.1 and R.sub.2 are each H, alkyl, alkenyl, cycloalkyl or aryl, or together represent an alkylene group optionally containing a heteroatom e.g. --O-- or --NH--; and --O- polycycle represents the residue of a polycyclic alcohol such as a sterol, preferably a 3-sterol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.