Patent · US Expired

Crystalline hydrochloride of (R)-(-)-2-(N-4-(1,1-dioxido-3-oxo-2,3-dihydro-benzisothiazol-2-yl-)-but yl!-aminomethyl)-chroman

US5830908A · kind A · utility

57Cited by

5References

3Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Alfons Grunenberg · Wuppertal, DE
Oliver Brehm · Wuppertal, DE
Michael Conrad · Wuppertal, DE
Dietrich Seidel · Feldafing, DE

Key dates

Filing date	Nov 19, 1996
Grant date	Nov 3, 1998
Priority date	—
Expiry date	Nov 19, 2016

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the crystalline form of the hydrochloride of the compound (R)-(-)-2-{N-4-(1,1-dioxido-3-oxo-2,3-dihydro-benzisothiazol-2-yl)-butyl! -aminomethyl}-chroman, which is present as a stable form at room temperature. The crystalline modification V of the hydrochloride is suitable in particular for the preparation of solid medicaments, in particular of medicaments for the treatment of neuronal degenerations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.