Boronic acid-contaning nucleic acid monomers
US5831046A · kind A · utility
8Cited by
8References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 5, 1996 |
| Grant date | Nov 3, 1998 |
| Priority date | — |
| Expiry date | Aug 5, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P19/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Modified nucleotides and polynucleotides which are useful in hybridization assays for the detection of target genes are provided. The modified polynucleotides contain at least one boronic acid moiety which is attached to a nucleotide base in a position which does not interfere with the hydrogen bonding capabilities of that base during duplex formation. The modified polynucleotides are typically formed from naturally occurring nucleotides and one or more modified nucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.