DNA encoding a novel kidney ATP-dependent potassium channels
US5831055A · kind A · utility
0Cited by
1References
1Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 9, 1996 |
| Grant date | Nov 3, 1998 |
| Priority date | — |
| Expiry date | Sep 9, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/705
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention comprises human DNA compositions, including cDNA clones, with full sequences, called, KIRK-2 and KIRK-3, encoding proteins that confer potassium channel activity to membranes or recipient cell lines. The DNA compositions include structural genes coding for the potassium channel proteins, expression and replication plasmids or vectors containing the structural genes and host cells expressing those genes. Methods of screening compounds for potassium channel modulating activity are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.