Steroid intermediate products and method of their production

US5831104A · kind A · utility

Assignee

• Jenapharm GmbH · DE

Inventors

• Sven Ring · Jena, DE
• Gerhard Teichmueller · Jena, DE
• Gisela Weber · Jena, DE
• Sigfrid Schwarz · Jena, DE
• Bernd Erhart · Kahla, DE
• Bernd Undeutsch · Jena, DE
• Harald Raethe · Jena, DE
• Peter Moellmann · Jena, DE
• Carmen Pfeiffer
• Hans-Joachim Palme · Jena, DE

Key dates

• Filing date: Sep 9, 1994
• Grant date: Nov 3, 1998
• Expiry date: Sep 9, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J11/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention is directed to novel steroid intermediate products of general formula I ##STR1## The steroid intermediate products which can be isolated according to the invention are suitable for the synthesis of 13-ethyl-11-methylene-18,19-bisnor-17.alpha.-pregn-4-en-20-in-17-ol (desogestrel). Further, processes for producing the steroid intermediate products of general formula I are described. The olefination of the 11-oxo steroids is carried out under the influence of ultrasound.