Marker at the estrogen receptor gene for determination of osteoporosis predisposition
US5834200A · kind A · utility
1Cited by
3References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 14, 1997 |
| Grant date | Nov 10, 1998 |
| Priority date | — |
| Expiry date | Jul 14, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method of determining predisposition to low or high bone mineral density and to development of osteoporosis of a patient, which comprises determining estrogen receptor polymorphism in linkage disequilibrium in a biological sample of said patient, wherein heterozygosity is associated with high bone density and homozygosity is associated with low bone density.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.