Screening methods for the identification of inducers and inhibitors of programmed cell death (apoptosis)
US5834216A · kind A · utility
15Cited by
1References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 6, 1995 |
| Grant date | Nov 10, 1998 |
| Priority date | — |
| Expiry date | Sep 6, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2510/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for the identification of inducers and inhibitors of apoptosis are described. The method exploits the finding that the exposure of cells to apoptotic stress and its concurrent shutdown of cellular protein synthesis is accompanied by phosphorylation of IF-2.alpha. and a novel protein termed p90.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.