Patent · US Expired

Quantification of nucleic acid

US5834255A · kind A · utility

80Cited by
2References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 7, 1995
Grant dateNov 10, 1998
Priority date
Expiry dateFeb 7, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/81
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed is a method of quantifying a target nucleic acid in a test sample by adding to the test sample a known number of molecules of a corresponding nucleic acid comprising a well-defined mutant sequence. Said mutant sequence being discriminatory from the target nucleic acid. Subsequently a competitive amplification reaction of the nucleic acid is performed after which quantification of the amplified nucleic acid is performed by a differential detection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.