Patent · US Expired

Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists

US5834468A · kind A · utility

16Cited by
17References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 2, 1996
Grant dateNov 10, 1998
Priority date
Expiry dateJul 2, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D237/24
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to substituted and unsubstituted (aryl- and heteroaryl-) alkyl-, alkyloxy-, alkylthio-, oxo-, thio-, and alkylamino!- heteroaryl and aryl!- alkylamino-, aminoalkyl-, alkyloxy-, and alkylthio!- aryl and heteroaryl compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof, which are useful as antagonists of the pain enhancing effects of E-type prostaglandins, to processes for the preparation of such compounds, to pharmaceutical compositions comprising such compounds, and to methods for treating pain comprising the administration of such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.