Hexa-cyclic compound
US5834476A · kind A · utility
40Cited by
4References
15Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 12, 1997 |
| Grant date | Nov 10, 1998 |
| Priority date | — |
| Expiry date | Dec 12, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.