Substituted dibenz (A F)azulenes and methods of preparation
US5834521A · kind A · utility
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12Claims
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Key dates
| Filing date | Aug 5, 1996 |
| Grant date | Nov 10, 1998 |
| Priority date | — |
| Expiry date | Aug 5, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Tetracyclic compounds having the following structure are described: ##STR1## wherein R.sub.1 -R.sub.10 are as defined. The tetracyclic compounds are capable of potent effects on steroid sensitive tissues and have demonstrated increased uterine weight, antiovulatory effects and potent steroid receptor binding. The compounds have therapeutic utility in reproductive applications such as fertility control, labor induction, ovulation induction and spermatogenesis. Methods for preparing the tetracyclic compounds from substituted indanones are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.