Ocular microsphere delivery system
US5837226A · kind A · utility
52Cited by
3References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 19, 1995 |
| Grant date | Nov 17, 1998 |
| Priority date | — |
| Expiry date | Sep 19, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6927
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained release drug delivery composition and a method of making same are provided which comprises microspheres containing a pharmaceutically active agent, a core of a ion-exchange resin and a polymeric coating completely surrounding the core wherein the coating is water-insoluble and hydrolytically stable in physiological environments. The coating is non-erodible in physiological environments and is characterized by a diffusion constant suitable for the pharmaceutical agent to diffuse from the core to an aqueous environment at a predetermined release rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.