Methods and compositions for cellular and metabolic engineering
US5837458A · kind A · utility
824Cited by
10References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 20, 1996 |
| Grant date | Nov 17, 1998 |
| Priority date | — |
| Expiry date | May 20, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/622
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is generally directed to the evolution of new metabolic pathways and the enhancement of bioprocessing through a process herein termed recursive sequence recombination. Recursive sequence recombination entails performing iterative cycles of recombination and screening or selection to "evolve" individual genes, whole plasmids or viruses, multigene clusters, or even whole genomes. Such techniques do not require the extensive analysis and computation required by conventional methods for metabolic engineering.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.