Sialyl lewis-x mimetics containing naphthyl backbones
US5837689A · kind A · utility
39Cited by
8References
33Claims
0Family size
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Key dates
| Filing date | Feb 21, 1996 |
| Grant date | Nov 17, 1998 |
| Priority date | — |
| Expiry date | Feb 21, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that possess selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs, derivatives, or mimics of these groups, such that sialic acid and fucose or their mimics are separated by a linker that permits binding between those groups and the selecting, such compounds being represented by the following general structural formula I: ##STR1##
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