Semi-interpenetrating polymer networks
US5837752A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1997 |
| Grant date | Nov 17, 1998 |
| Priority date | — |
| Expiry date | Jul 17, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/923
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Compositions for bone repair have been developed based on linear hydrophobic degradable polymers and monomers or macromers, at least one of which includes an anhydride linkage. The monomers and/or macromers crosslink each other but not to the linear polymer to form semi-interpenetrating networks. The compositions can include various excipients, therapeutic and/or diagnostic agents. The compositions can be polymerized in the presence of dissolvable particles such as inorganic salts and proteinaceous materials to provide a porous polymer network. The compositions can be injected into a patient and polymerized in situ or can be polymerized ex vivo and implanted. When polymerized ex vivo, the composition can be shaped into various articles, such as pins, screws, and hollow tubes, which can be used to repair broken bones.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.