Protein adsorption by very dense porous zirconium oxide particles in expanded beds

US5837826A · kind A · utility

Assignee

• Regents of the University of Minnesota · US

Inventors

• Michael C. Flickinger · Windom, US
• Michael J. Robichaud · Minneapolis, US
• John E. Morris · Minneapolis, US
• Colleen M. Griffith · Broomfield, US
• Michael J. Annen · Hudson, US
• Peter W. Carr · Minneapolis, US
• Christopher A. Dunlap · Dunlap, US

Key dates

• Filing date: Feb 27, 1995
• Grant date: Nov 17, 1998
• Expiry date: Feb 27, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/811
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Porous zirconia particles of specific gravity of 2.5-3.5 g/cm.sup.3 and mean particle sizes of 30-400 .mu.m can be synthesized using oil emulsion methods from colloids and used for protein adsorption in stable expanded beds. Expanded beds of less than 1.0 settled bed height to diameter (approximately 10 ml bed volume) are stable at linear fluid velocities of at least about 100 cm/hour.