Method of detecting amplified nucleic sequences in cells by flow cytometry
US5840478A · kind A · utility
3Cited by
5References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 18, 1994 |
| Grant date | Nov 24, 1998 |
| Priority date | — |
| Expiry date | May 18, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N15/14
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The field of this invention is the detection and isolation of specific amplified DNA sequences by flow cytometry. More particularly, this invention relates to the detection of these specific amplified DNA sequences in cells so as to allow quantitation of viral burden of patients infected with a virus. The method is particularly adapted to detection of HIV-1 proviral DNA sequences and the assessment of activity of the virus in a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.