Patent · US Expired

Methods for diagnosis of conditions associated with elevated levels of telomerase activity

US5840495A · kind A · utility

2Cited by
3References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateNov 24, 1998
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/115831
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.