Method for specific silencing of genes by DNA methylation
US5840497A · kind A · utility
9Cited by
0References
8Claims
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Assignee
Inventor
Key dates
| Filing date | Sep 29, 1997 |
| Grant date | Nov 24, 1998 |
| Priority date | — |
| Expiry date | Sep 29, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3341
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for the silencing of specific genes by DNA methylation. The method involves introducing into a cell a single stranded oligonucleotide containing 5-methyl deoxycytosine. The single stranded oligonucleotide has a sequence complementary to a portion of the DNA sequence of the gene to be silenced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.