Modified ligands for receptor tyrosine kinases
US5840687A · kind A · utility
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25Claims
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Assignee
Inventors
Key dates
| Filing date | Feb 2, 1995 |
| Grant date | Nov 24, 1998 |
| Priority date | — |
| Expiry date | Feb 2, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides for synthetic ligands that bind to class I receptor tyrosine kinases. The ligands are analogous in structure to naturally occurring ligands. The modified ligands however, have eliminated the mid-sequence (B) domain present in the native ligands and replaced it with a peptide bridge which links the amino (A) and carboxy (C) domains.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.