Eating suppressant peptides
US5840688A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Mar 22, 1995 |
| Grant date | Nov 24, 1998 |
| Priority date | — |
| Expiry date | Mar 22, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peptides corresponding to specific portions of the apolipoprotein A-IV (apo A-IV) are provided. Most of the peptides correspond to the amino terminal region of apo A-IV. In addition, those peptides corresponding to the amino terminal portion of apo A-IV substantially correspond to a fundamental repeat unit of twenty two amino acids comprising: PA1 DYFTQLSNNAKEAVEQLQKTDV SEQ ID NO:88 as well as homologs and analogs thereof. The peptides have eating suppressant properties when administered centrally or peripherally. The peptides may be used in compositions and methods for suppressing the appetite and controlling food intake.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.