Pancreatic islet cell antigens obtained by molecular cloning
US5840836A · kind A · utility
1Cited by
1References
26Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 5, 1994 |
| Grant date | Nov 24, 1998 |
| Priority date | — |
| Expiry date | May 5, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pancreatic islet cell antigens (ICA) that bind with antibodies found in the sera of patients afflicted with insulin-dependent (Type I) diabetes mellitus (IDDM). ICA proteins are expressed by recombinant cloning vehicles comprising DNA inserts isolated from islet cells. Full sequence native ICA proteins, or protein or peptide fragments thereof, can be used in the diagnosis of IDDM and in detecting or blocking human immunoglobulin, T-cells, or B-cells involved in IDDM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.