Compounds for treating infectious diseases

US5840893A · kind A · utility

Assignee

• The Picower Institute for Medical Research · US

Inventors

• Michael Bukrinsky · Glenwood Landing, US
• Anthony Cerami · Stratford, US
• Peter C. Ulrich · Old Tappan, US
• Bradley Berger · Greenlawn, US

Key dates

• Filing date: Jan 5, 1996
• Grant date: Nov 24, 1998
• Expiry date: Jan 5, 2016

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There is disclosed compound according to the formula: ##STR1## wherein A, independently,=CH.sub.3 or CH.sub.2 CH.sub.3, P=1 or 2; and ##STR2## wherein X=NH.sub.2, CH.sub.3 or CH.sub.2 CH.sub.3 ; X'=CH.sub.3 or CH.sub.2 CH.sub.3 ; Y=NH.sub.2, NHCH.sub.3, N(CH.sub.3).sub.2 ; and Z=H, CH.sub.3 or CH.sub.2 CH.sub.3 ; or ##STR3## wherein Y' and Z', independently,=H, NH.sub.2, NHCH.sub.3, N(CH.sub.3).sub.2 or N.sup.+ (CH.sub.3).sub.3 ; Q is N or CH; and salts thereof.