Method of treatment of infected tissues
US5843473A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 1992 |
| Grant date | Dec 1, 1998 |
| Priority date | — |
| Expiry date | Mar 27, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/5537
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating a site of systemic infection which includes administering a therapeutic compound entrapped in liposomes. Also included is a liposomal composition and a method of preparing a liposomal composition for use in concentrating a therapeutic compound to an infected region via the bloodstream. The liposomes, which contain the agent in entrapped form, are composed of vesicle-forming lipids, a vesicle-forming lipid derivatized with hydrophilic biocompatible polymer, and have sizes in a selected size range between 0.07 and 0.2 microns. After parenteral administration, the liposomes are selectively taken up by the infected region within 24-48 hours, for release of entrapped compound into the infected region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.