Recombinant production of novel polyketides

US5843718A · kind A · utility

Assignees

• The Board of Trustees of the Leland Stanford Junior University · US
• The John Innes Institute · GB

Inventors

• Chaitan Khosla · Stanford, US
• David A. Hopwood · Norwich, GB
• Susanne Ebert-Khosla · Stanford, US
• Robert McDaniel · Palo Alto, US
• Hong Fu · Chongqing, CN

Key dates

• Filing date: Mar 31, 1997
• Grant date: Dec 1, 1998
• Expiry date: Mar 31, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P19/62
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Novel polyketides and novel methods of efficiently producing both new and known polyketides, using recombinant technology, are disclosed. In particular, a novel host-vector system is described which is used to produce polyketide synthases which in turn catalyze the production of a variety of polyketides.