Patent · US Expired

Prevention of viral infection by the induction of apoptosis and/or the use of an antiviral gene, hem1

US5843736A · kind A · utility

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4Claims
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Assignee

Inventor

Key dates

Filing dateMay 26, 1994
Grant dateDec 1, 1998
Priority date
Expiry dateMay 26, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2710/14122
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed is a new, effective and general methodology to prevent viral infection, which methodology is divided into two parts: 1) induction of the apoptosis (programmed cell death) of a host upon viral infection to block viral reproduction; and 2) the use of an apoptosis triggering gene, the persistency-associated gene 1 (pag1, now renamed as hem1 in light of the position thereof in the restriction map of the Hz-1 viral genome) to prevent the viral infection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.