Ring-expanded nucleosides and nucleotides
US5843912A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Aug 23, 1995 |
| Grant date | Dec 1, 1998 |
| Priority date | — |
| Expiry date | Aug 23, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/052
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compositions comprising analogues of purine nucleosides containing a ring-expanded ("fat") heterocyclic ring, in place of purine, and an unmodified or modified sugar residue, pharmaceutically acceptable derivatives of such compositions, as well as methods of use thereof. In particular, these compositions may be utilized in the treatment of certain cancers, bacterial, fungal, parasitic, and viral infections, including, but not limited to, Acquired Immunodeficiency Syndrome (AIDS) and hepatitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.