DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents
US5843937A · kind A · utility
24Cited by
1References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 23, 1996 |
| Grant date | Dec 1, 1998 |
| Priority date | — |
| Expiry date | May 23, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel DNA alkylating agents and the prodrugs of these agents which are useful as antitumor agents and DNA labelling agents. The compounds are hydroxy dihydrobenzindole oligopeptides and prodrugs thereof wherein the monomeric constituents are derived from monocyclic or bicyclic heterocyclic aromatic residues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.