Gene transfer therapy delivery device and method
US5846225A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 19, 1997 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Feb 19, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M5/3298
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A gene transfer delivery apparatus and method includes a plurality of syringes retained in a syringe-retaining portion. Each syringe contains a predetermined quantity of treatment solution. The treatment solution may be expelled through a needle on the end of each syringe by depressing the syringe plunger associated with each syringe. The syringe-retaining portion of the delivery device is connected to a plunger portion which contains a main plunger capable of depressing the syringe plungers simultaneously. Since the syringe plungers are depressed uniformly, the delivery device allows for the precise injection of a fixed volume of fluid at plural locations and at a predetermined depth. A spring-biased platen is mounted on the device for flattening the tissue prior insertion of the needles into the tissue. A method of using the delivery device for treatment of ischemic heart disease by gene therapy is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.