Perfluoroalkylated amphiphilic phosphorus compounds: preparation and biomedical applications
US5846516A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 3, 1992 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Jun 3, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Perfluoroalkylated amphiphilic phosphorus compounds, corresponding to the formulae: ##STR1## wherein V is O or S; PA1 R.sup.1, R.sup.2 and R.sup.3 are H or substituted or unsubstituted perfluoroalkylated or hydrocarbon radicals; provided that PA1 R.sup.1, R.sup.2 or R.sup.3 is a perfluoroalkylated radical; and Y and Z are radicals which can bear a part derived from a sugar, a polyol, or a hydrophilic polymer such as polyethyleneglycol, a perfluoroalkylated part or a part derived from a pharmaceutically active molecule, and method for their preparation and use. These compounds can be included in preparations, emulsions, dispersions, gels, microemulsions, notably for biomedical uses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.