Structural phosphoprotein (PP150) of human cytomegalovirus, and the preparation and use thereof

US5846733A · kind A · utility

Assignee

• Behring Diagnositcs GmbH · DE

Inventors

• Gerhard Jahn · Neunkirchen, DE
• Birgit-Christine Scholl · Uttenreuth, DE
• Michael Broker · Marburg, DE
• Michael Mach · Erlangen, DE
• Bernhard Fleckenstein · Wiesenthau, DE
• Bernd Traupe · Hamburg, DE

Key dates

• Filing date: Apr 28, 1995
• Grant date: Dec 8, 1998
• Expiry date: Apr 28, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/16122
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The phosphorylated structural protein of molecular weight about 150 kd (pp 150) of human cytomegalovirus (HCMV) is highly immunogenic and is reliably recognised by human antisera. This protein can, after assignment and sequencing of the gene, be prepared, in whole or in immunogenic sections, by gene manipulation. Proteins of this type are suitable as reagents, for example in an ELISA, and as constituents of vaccines.