Methods for hard-tagging an encoded synthetic library

US5846839A · kind A · utility

Assignee

• Glaxo Group Limited · GB

Inventors

• Mark A. Gallop · Santa Clara, US
• Eric M. Gordon · Pennington, US
• Zhi-Jie Ni · Emeryville, US
• Derek Maclean · Los Altos, US
• Christopher P. Holmes · Sunnyvale, US
• William Fitch · Palo Alto, US
• Nikhil Shah · Yardley, US

Key dates

• Filing date: Dec 22, 1995
• Grant date: Dec 8, 1998
• Expiry date: Dec 22, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B70/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed are chemical encryption methods for determining the structure of compounds formed in situ on solid supports by the use of specific amines tags which, after compound synthesis, can be deencrypted to provide the structure of the compound found on the support.