Oral antifungal composition
US5846971A · kind A · utility
46Cited by
9References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 20, 1997 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Jun 20, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/497
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition comprising: PA1 i) substantially inert beads; wherein said beads are coated with PA1 ii) an antifungal agent which is (-)-(2R-cis)-4-4-4-4--5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-tr iazol-1-ylmethyl)furan-3-yl!methoxy!phenyl!-1-piperazinyl!phenyl!-2,4-dihyd ro-2-(S)-1-ethyl-2(S)-hydroxypropyl!-3H-1,2,4-triazol-3-one; PA1 iii) a binder to enables the antifungal compound to adhere to said beads. The composition enables the antifungal compound, which has very low water solubility, to have enhanced bioavailability in mammals, such as humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.