Bicyclic pyrimidine derivatives and their use as anti-coagulants
US5846972A · kind A · utility
47Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1997 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Jun 17, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to bicyclic pyrimidine derivatives of the following formulae: ##STR1## where A is --O--and Z.sup.1,Z.sup.2,R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6,R.sup.7 are defined herein. These compounds are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing these compounds and methods of using the compounds to treat disease-states characterized by thrombotic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.