Benzothiazolone derivatives

US5846989A · kind A · utility

Assignee

• Astra Pharmaceuticals Limited. · GB

Inventors

• Roger Bonnert · Loughborough, GB
• Roger Brown · Coalville, GB
• Peter Cage · Loughborough, GB
• Francis Ince · Loughborough, GB
• Garry Pairaudeau · Coalville, GB

Key dates

• Filing date: Feb 7, 1997
• Grant date: Dec 8, 1998
• Expiry date: Feb 7, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of formula I, including optical isomers thereof, ##STR1## wherein X represents --SO.sub.2 NH-- or --NHSO.sub.2 --, PA1 p, q and r independently represent 2 or 3, PA1 Y represents thienyl optionally substituted by alkyl or halogen, or phenylthio- or phenyl optionally substituted by alkyl or halogen, and PA1 each R independently represents H or alkyl, and pharmaceutically acceptable salts, esters and amides thereof.