Polypeptide capable of differentiating and maturing malignant cells into normal cells or capable of accelerating the formulation of erythroblasts
US5847078A · kind A · utility
64Cited by
4References
1Claims
0Family size
Inventors
Key dates
| Filing date | Mar 3, 1995 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Mar 3, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A physiologically active polypeptide, BUF-3, having the ability to differentiate and maturate human leukemia cells into normal cells and of accelerating the formation of erythroblasts is disclosed. The polypeptide has a molecular weight of 16.+-.1 Kd as determined by SDS-electrophoresis in the presence of 1% mercaptoethanol, or 25.+-.1 Kd, as determined by SDS-electrophoresis in the absence of mercaptoethanol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.